The platelet rich fibrin is a three-dimensional structure, the matrix of which is fibrin.
High concentrations are located in the spaces of the three-dimensional fibrin network
non-activated, functional, intact platelets, white blood cells and stem cells.

Together with fibrin, all these elements form a matrix – a spatial structure that continuously and in the long term stimulates the plates to release growth factors, cytokines and effectively directs the migration of mesenchymal stem cells to the site of body injury.

Growth factors and stem cells released from the space of the fibrin grid strongly stimulate the biological renewal of tissues.
The main indications in aesthetic medicine are: filling of wrinkles and tissue defects, volumetry, revitalization of the face, neck, cleavage, hands and scar reduction.